What are the sexual side effects of antidepressants and what can I do about them?
Depression
Sexual side effects are among the most common and distressing side effects of antidepressants, affecting 40-65% of people taking these medications.
Sexual side effects are among the most common and distressing side effects of antidepressants, affecting 40-65% of people taking these medications. Understanding these effects and knowing that there are solutions can help you maintain both your mental health treatment and your sexual wellbeing.
Common sexual side effects include decreased libido or interest in sex, difficulty becoming aroused or maintaining arousal, delayed or absent orgasm, reduced intensity of orgasms, and erectile dysfunction in men. These effects can occur with most classes of antidepressants but are particularly common with SSRIs and SNRIs.
These side effects typically develop within the first few weeks of starting an antidepressant and unfortunately don't usually improve on their own over time like some other side effects do. For many people, sexual side effects persist as long as they're taking the Psychiatric medication, which can create a difficult choice between mental health and sexual health.
The first step is to discuss these side effects openly with your prescribing physician. Many people feel embarrassed talking about sexual problems, but these are medical side effects that deserve attention and treatment. Your doctor has likely dealt with this issue many times and can offer various solutions.
Timing and dosage adjustments can sometimes help. Taking your Psychiatric medication at a different time of day, reducing the dose slightly (if clinically appropriate), or taking "drug holidays" before planned sexual activity are options some doctors might suggest, though these approaches require careful medical supervision.
Switching to a different antidepressant with lower rates of sexual side effects is often the most effective solution. Bupropion (Wellbutrin) is known for having minimal sexual side effects and sometimes even enhancing libido. Mirtazapine (Remeron) and some of the newer antidepressants like vilazodone (Viibryd) or vortioxetine (Trintellix) may also have fewer sexual side effects.
Adding medications to counteract sexual side effects is another option. Bupropion can be added to your current antidepressant to help with libido and arousal. For men with erectile dysfunction, medications like sildenafil (Viagra) or tadalafil (Cialis) can be effective. Some doctors prescribe buspirone, which may help with sexual side effects in some people.
Lifestyle approaches can also help manage sexual side effects. Regular exercise improves blood flow and can enhance sexual function. Psychological stress reduction techniques like mindfulness" target="_blank" rel="noopener noreferrer">Mindfulness or yoga can help with arousal and enjoyment. Open healthy relationships/improving-communication" class="internal-link">communication skills" target="_blank" rel="noopener noreferrer">Communication with your partner about these challenges can reduce performance worry disorder and help you explore alternative forms of intimacy.
Consider working with a sex therapist or counselor who understands Psychiatric medication-related sexual dysfunction. They can help you and your partner navigate these challenges and develop strategies for maintaining intimacy while managing the side effects.
Don't stop taking your antidepressant without medical supervision, even if sexual side effects are bothersome. Sudden discontinuation can cause withdrawal symptoms and potentially dangerous rebound Major depressive disorder. Work with your doctor to find solutions that allow you to maintain your mental health treatment while addressing sexual concerns.
Be patient with the process of finding solutions. It may take time to find the right Psychiatric medication adjustment or alternative that works for both your Major depressive disorder and your sexual health. Keep track of how different approaches affect both your mood and sexual function to help guide treatment decisions.
Remember that sexual health is an important component of overall wellbeing and quality of life. You don't have to choose between treating your Major depressive disorder and maintaining a healthy sex life—with the right approach and medical support, it's often possible to address both concerns effectively.
If your doctor dismisses your concerns about sexual side effects or seems unwilling to explore solutions, consider seeking a second opinion from another psychiatrist or your primary care physician.